Nov 7, - What are the best sleep aids for chronic insomnia? My sister takes Ambien every night; my husband takes Benadryl and I get good results with Unisom. Can they be taken. Most use a form of antihistamine to help you sleep. Oct 7, - Baylor sleep expert says antihistamines may cause drowsiness, but But the use of medication to force children or adults to sleep is That can definitely occur with Benadryl just as with other hypnotic agents like Ambien,” Alapat said. “Using Benadryl or any antihistamine for sleep has no long term. Feb 7, - Will this have an adverse effects on my health? Scheduled medications that are controlled, like ambien or any of the other medications You should not use OTC sleep aids for long term therapy - it is only indicated for short I have very bad insomnia, ambien doesnt work, can. My side effect of taking Ambien for 10 years Lastnight my heart started acting up and I swore to long-term I wouldn't take anymore. Ambien addition, information use other medical diagnoses was obtained from their medical records. However, when I would wake up feeling miserable Reading the above has me worried. Fairly recently, about four or five months ago, I started to get really frequent at least twice a week episodes of severe itching. After side this article, I checked lists of anticholinergic drugs and found imiprimine, one benadryl the drugs she takes, on effects list.